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The concentration at which a maximal effect occurs cannot be measured accurately; however, that eliciting a half-maximal effect (EC50) is readily determined. It typically corresponds to the inflection point of the concentration– response curve in a semilogarithmic plot (log concentration on abscissa).
From ampules for multiple or single use, the solution is aspirated via a needle into a syringe. The cartridge ampule is fitted into a special injector that enables its contents to be emptied via a needle. An infusion refers to a solution being administered over an extended period of time. Solutions for infusion must meet the same standards as solutions for injection. |
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