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Drugs can be sprayed in aerosol form onto mucosal surfaces of body cavities accessible from the outside (e.g., the respiratory tract. An aerosol is a dispersion of liquid or solid particles in a gas, such as air. An aerosol results when a drug solution or micronized powder is reduced to a spray on being driven through the nozzle of a pressurized container.
Zanaflex (Tizanidine Hydrochloride) is a short-acting drug indicated for the management of spasticity. Because of the short duration of effect, treatment with Zanaflex (Tizanidine Hydrochloride) should be reserved for those daily activities and times when relief of spasticity is most important.

 

This structural element is unimportant for efficacy; even drugs containing a methylene bridge, such as chlorpromazine (p. 236) or imipramine (p. 230), would exert a local anesthetic effect with appropriate application. Ester-type local anesthetics are subject to inactivation by tissue esterases. This is advantageous because of the diminished danger of systemic intoxication.
This second neuron does not synapse with only a single cell in the effector organ; rather, it branches out, each branch making en passant contacts with several cells. At these junctions the nerve axons form enlargements (varicosities) resembling beads on a string.

 

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