Drug Name Anafranil

Nicotinic acid and its derivatives (pyridylcarbinol, xanthinol nicotinate, acipimox) activate endothelial lipoprotein lipase and thereby lower triglyceride levels. At the start of therapy, a prostaglandin-mediated vasodilation occurs (flushing and hypotension) that can be prevented by low doses of acetylsalicylic acid.
Hypnotics fall into different categories, including the benzodiazepines (e. g. , triazolam, temazepam, clotiazepam, nitrazepam), barbiturates (e. g. , hexobarbital, pentobarbital), chloral hydrate, and H1-antihistamines with sedative activity. Benzodiazepines act at specific receptors.

 

Closely related chemically to amphetamine are the so-called appetite suppressants or anorexiants, such as fenfluramine, mazindole, and sibutramine. These may also cause dependence and their therapeutic value and safety are questionable.
Other adverse effects are increased photosensitivity of the skin and hepatic damage, mainly after i. v. administration. The broad-spectrum antibiotic chloramphenicol is completely absorbed after oral ingestion. It undergoes even distribution in the body and readily crosses diffusion barriers such as the blood-brain barrier.