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In case this treatment fails (no effect within 30 min, administration of morphine, if needed in combination with an antiemetic to prevent morphine-induced vomiting, is indicated. If ECG signs of myocardial infarction are absent, the patient is stabilized by antianginal therapy (nitrates, ?- blockers) and given ASA and heparin.
The antiparkinsonian effects of selegiline may result from decreased dopamine inactivation (enhanced levodopa response) or from neuroprotective mechanisms (decreased oxyradical formation or blocked bioactivation of an unknown neurotoxin). Inhibitors of catechol-O-methyltransferase (COMT). L-Dopa and dopamine become inactivated by methylation.

 

The treatment of choice (after the cause of bleeding has been found and eliminated) consists of the oral administration of Fe2+ compounds, e.g., ferrous sulfate (daily dose 100 mg of iron equivalent to 300 mg of FeSO4, divided into multiple doses). Replenishing of iron stores may take several months.
The uterine relaxant effect of ?2-adrenoceptor agonists, such as terbutaline or fenoterol, can be used to prevent premature labor. Vasodilation with a resultant drop in systemic blood pressure results in reflex tachycardia, which is also due in part to the ?1-stimulant action of these drugs. Cardiostimulation.

 

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