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ACE inhibitors augment the effectiveness of diuretics by preventing this counter-regulatory response. The smallest functional unit of the kidney is the nephron. In the glomerular capillary loops, ultrafiltration of plasma fluid into Bowman’s capsule (BC) yields primary urine.
Predictable effects that derive from the known pharmacological drug properties. Examples are: masculinization of the female fetus by androgenic hormones; brain hemorrhage due to oral anticoagulants; bradycardia due to ?-blockers. 2. Effects that specifically affect the developing organism and that cannot be predicted on the basis of the known pharmacological activity profile. |
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