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With the long-acting substances marketed initially, this problem was less obvious in comparison with other dependence- producing drugs because of the delayed appearance of withdrawal symptoms.
Streptomycin and kanamycin are used predominantly in the treatment of tuberculosis. Note on spelling: -mycin designates origin from Streptomyces species; -micin (e. g. , gentamicin) from Micromonospora species. 2. Chloramphenicol inhibits peptide synthetase. It has bacteriostatic activity against a broad spectrum of pathogens.

 

Systemically administered epinephrine is important in the treatment of anaphylactic shock for combating hypotension. Bronchodilation. ?2-Adrenoceptor- mediated bronchodilation (e. g. , with terbutaline, fenoterol, or salbutamol) plays an essential part in the treatment of bronchial asthma (p. 328). Tocolysis.
It is stored instead of NE, but is unable to mimic the functions of the latter. In addition, it stabilizes the axonal membrane, thereby impeding the propagation of impulses into the sympathetic nerve terminals. Storage and release of epinephrine from the adrenal medulla are not affected, owing to the absence of a re-uptake process.

 

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